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PHOTOCHEMICAL PROPERTIES AND CYTOTOXICITY OF TiO<i>2</i> NANOPARTICLES DEPENDING ON THE DEGREE OF AGGLOMERATION

N. A. Lee, M. Yoon, N. W. Song

Abstract

The purpose of this paper is to evaluate the photocatalytic activity and the cytotoxicity of the primary TiO<sub>2</sub> nanoparticles (P-TiO<sub>2</sub> NPs) comparing with aggregated TiO<sub>2</sub> nanoparticles (A-TiO<sub>2</sub> NPs). A-TiO<sub>2</sub> NPs were suspended in pH 8 phosphate buffer and stabilized after magnetic stirring. P-TiO<sub>2</sub> NPs were isolated from A-TiO<sub>2</sub> NPs by using centrifuge method. The photocatalytic activity was measured by observing the photocatalytic oxidation rate of NADH and the cytotoxicity assessment was evaluated by using the MTT assay. The oxidation rate of NADH in ATiO<sub>2</sub> NP suspension was slightly higher than that in P-TiO<sub>2</sub> NP suspension. P-TiO<sub>2</sub> NP showed about 20% higher cytotoxicity than A-TiO<sub>2</sub> NP at the concentration of 0.3 mg/ml.

Keywords
agglomerated TiO2 NP, primary TiO2 NP, photocatalytic activity, cytotoxicity
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IMEKO-WC-2012-TC13-P6.pdf
DOI
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IMEKO TC
TC13 - Measurements in Biology and Medicine

Event details

Event
XX IMEKO World Congress
Place
Busan, REPUBLIC of KOREA
Time
9 September 2012 - 12 September 2012
Website
http://imeko2012.kriss.re.kr

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