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Development of metabolomics for Alternaria toxins as a model for risk assessment of mycotoxins

Gotthardt, M., Kanawati, B., Schmitt-Kopplin, P., Rychlik, M.

Abstract

A stable isotope dilution LC-MS/MS method was developed for the Alternaria toxins alternariol (AOH), alternariol monomethylether (AME) and tenuazonic acid (TeA) in herbs. Tentoxin (TEN) was quantified using matrix calibration. Solid phase extraction was applied for sample purification. Limits of detection (LOD) and quantification (LOQ), recoveries and intra- and interday precisions were determined for a comprehensive validation. The method was used to evaluate the mycotoxin contamination in various herbs and infusions.

Keywords
Alternaria toxins, SIVA, LC-MS/MS
Download
IMEKO-TC23-2017-091.pdf
DOI
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IMEKO TC
TC23 - Metrology in Food and Nutrition

Event details

Event
3rd IMEKOFOODS Conference
Technical Committee
TC23
Email
imekofoods3@gmail.com
Place
Thessaloniki, GREECE
Time
1 October 2017 - 4 October 2017

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