MICROSYSTEM FOR BIOLOGICAL ANALYSIS BASED ON MAGNETORESISTIVE SENSING

J. Germano, M. S. Piedade, L. Sousa, T. M. Almeida, P. Lopes, F. A. Cardoso, H. A. Ferreira, P. P. Freitas

Abstract

This paper presents a microsystem for biomolecular recognition (DNA, enzymes) based on a biochip, which uses magnetic field arraying of magnetically tagged biomolecules and high sensitivity sensors for single biomolecule detection. The microsystem provides the electronic circuitry for addressing, reading out and sensing each of the 16 x 16 magnetoresistive sensors that compose the biochip. A prototype of the microsystem was developed and experimental results show that it is able of nanoparticle detection and, consequently, be used for magnetic labelled based bioassays.

Keywords

miscrosystem, biochip, biomolecular recognition

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PWC-2006-TC13-012u.pdf

DOI

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IMEKO TC

TC13 - Measurements in Biology and Medicine

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