Metrology for Drug Delivery project – results and impact

Elsa Batista, Hugo Bissig, John Morgan, Anders Niemann, Annemoon Timmerman, Florestan Ogheard

Abstract

This paper presents the major impacts of the work developed in EMPIR Project - MeDD II, Metrology for Drug Delivery in the reference standards used for flow rate determination of drug delivery devices and the results obtained in each work package, with a special focus on the primary standards developed by the partners using different technologies. These new primary standards were validated via an inter-laboratory comparison using two different type of flow meters and a precision syringe pump, in a range from 1500 nL/min down to 5 nL/min. This inter-comparison was performed between nine participating laboratories, each with different methodologies, measurement principles, flow ranges,operating conditions, and measurement uncertainty values.

Keywords

Drug delivery; New primary standard; Inter-laboratory comparison

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IMEKO-TC9-2019-146.pdf

DOI

10.21014/tc9-2022.146

IMEKO TC

TC9 - Flow Measurement

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