DEVELOPMENT OF A CERTIFIED REFERENCE MATERIAL FOR NICOTINAMIDE IN INFANT FORMULA

Jun Liu, Ting Huang, Wei Zhang, Yang Liu
Abstract:
Nicotinamide, one kind of Vitamin B, plays an important role for humans. To ensure quality control of nicotinamide in infant formula, a Certified Reference Material for nicotinamide in infant formula is being prepared in China for the first time. Studying on the procedure of sample preparation and HPLC analysis with different detectors like UV and MS, HPLC-UV and HPLC-IDMS are selected as the value assignment methods. And HPLC-IDMS method was validated in the international comparison CCQM-P78 and CCQM-K62. Homogeneity and stability are discussed in this paper as well.
Keywords:
nicotinamide, infant formula, certified reference material
Download:
IMEKO-WC-2009-TC23-159.pdf
DOI:
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Event details
Event name:
XIX IMEKO World Congress
Title:

Fundamental and Applied Metrology

Place:
Lisbon, PORTUGAL
Time:
06 September 2009 - 11 September 2009