EVALUATION OF OPTICAL SIGNALS FOR DNA CHAIN ANALYSIS

A. Cysewska-Sobusiak, M. Boltrukiewicz
Abstract:
The molecular complementarity of the two strands of the DNA double helix makes it possible to model changes in DNA sequences manifesting by related changes in their melting temperature, thermodynamic data and optical properties. The subject of the paper is focused on metrological problems connected with modeling of a virtual integrated oligonucleotide library, basing on the analysis of fluorescence signals to be obtained as a result of hybridization.
Keywords:
oligonucleotide biooptics, modeling and simulation
Download:
IMEKO-WC-2000-TC13-P331.pdf
DOI:
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Event details
Event name:
XVI IMEKO World Congress
Title:

Measurement - Supports Science - Improves Technology - Protects Environment ... and Provides Employment - Now and in the Future

Place:
Vienna, AUSTRIA
Time:
25 September 2000 - 28 September 2000