Q.C. OF BLOOD CHEMICAL ANALYSIS BY MICHAELIS MENTEN FACTOR

Y. Iwaki, T. Inamura, K. Kariya
Abstract:
Measured data of blood chemical analysis have dispersion results in themselves, but if a statistical analysis is applied to the results, an effective factor is obtained on accuracy quality control. As a method, there is the one which confirms the existence of abnormal reaction products by Michalies-Menten factor. This factor expresses the relation between the change of concentration of reagent and measurement data, and also the factor discriminates the good or bad of blood test reagent. And in this study, the effect of deposit days of the factor was studied. Then in this study, the reagent of Radioimmunoassay (RIA) was selected as an experiment object. The RIA is a kind of blood chemical analysis.
In this paper, the accuracy of calibration curve of RIA was studied, and the good or bad of calibration curve was discriminated by using Michaelies-Menten factor. And then the discussion of time series variation data that the calibrator reagent changes in a deposit day was done.
Keywords:
radioimmunoassay ISO standard rule, WHO standard rule, quality control
Download:
IMEKO-WC-2000-UNC-P508.pdf
DOI:
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Event details
Event name:
XVI IMEKO World Congress
Title:

Measurement - Supports Science - Improves Technology - Protects Environment ... and Provides Employment - Now and in the Future

Place:
Vienna, AUSTRIA
Time:
25 September 2000 - 28 September 2000