Development of metabolomics for Alternaria toxins as a model for risk assessment of mycotoxins

Gotthardt, M., Kanawati, B., Schmitt-Kopplin, P., Rychlik, M.
Abstract:
A stable isotope dilution LC-MS/MS method was developed for the Alternaria toxins alternariol (AOH), alternariol monomethylether (AME) and tenuazonic acid (TeA) in herbs. Tentoxin (TEN) was quantified using matrix calibration. Solid phase extraction was applied for sample purification. Limits of detection (LOD) and quantification (LOQ), recoveries and intra- and interday precisions were determined for a comprehensive validation. The method was used to evaluate the mycotoxin contamination in various herbs and infusions.
Keywords:
Alternaria toxins, SIVA, LC-MS/MS
Download:
IMEKO-TC23-2017-091.pdf
DOI:
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Event details
IMEKO TC:
TC23
Event name:
3rd IMEKOFOODS Conference
Title:

Metrology Promoting Standardization and Harmonization in Food and Nutrition

Place:
Thessaloniki, GREECE
Time:
01 October 2017 - 04 October 2017