MAGNETORESISTIVE BIOSENSOR MODELLING FOR BIOMOLECULAR RECOGNITION

T. M. Almeida, M. S. Piedade, P. C. Lopes, L. Sousa, J. Germano, F. Cardoso, H. A. Ferreira, P. P. Freitas
Abstract:
This paper presents the modelling of a magnetic biosensor included on a hand held microsystem based on a fully integrated magnetoresistive biochip for biomolecular recognition (DNA hybridisation, antibody antigen interaction, etc.). The biochip uses magnetic field arraying of magnetically tagged biomolecules and high sensitivity sensors which can be used to detect single or few biomolecules. The biosensor has an matrix-array structure and each biosensor site consists of a thin film diode in series with a magnetic tunnel junction. Schottky and pin diodes are used as temperature sensors and switching devices, although this paper specially emphasises pin diodes characterisation. A complete theoretical model characterising biosensor electrical, temperature and magnetic behaviour is derived and experimental results are provided.
Keywords:
biosensor modelling, biochip, magnetoresistive sensor, biomolecular recognition
Download:
PWC-2006-TC13-028u.pdf
DOI:
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Event details
Event name:
XVIII IMEKO World Congress
Title:

Metrology for a Sustainable Development

Place:
Rio de Janeiro, BRAZIL
Time:
17 September 2006 - 22 September 2006